Emerging Trends in Noninvasive Insulin Delivery
نویسندگان
چکیده
منابع مشابه
Concept, strategies, and feasibility of noninvasive insulin delivery.
OBJECTIVE To comprehensively review the progress to date on the development of alternative routes for insulin delivery. RESEARCH DESIGN AND METHODS Study data were collected through a Medline review. RESULTS Proof of principle has been established for many routes of administration including dermal, nasal, oral, buccal, and pulmonary insulin delivery. CONCLUSIONS Of all the approaches to d...
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Address for correspondence: William T. Cefalu Department of Medicine University of Vermont, College of Medicine UHC Campus,Arnold 3433 One South Prospect Street Burlington,Vermont 05401 United States Telephone: (802) 847-8901 E-mail: william.cefalu@ uvm.edu 43 noninvasive insulin delivery systems INTRODUCTION Since its discovery, insulin has been the mainstay of treatment for patients with type...
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The use of ultrasound for the delivery of drugs to, or through, the skin is commonly known as sonophoresis or phonophoresis. The use of therapeutic and high frequencies of ultrasound (≥0.7MHz) for sonophoresis (HFS) dates back to as early as the 1950s, while low-frequency sonophoresis (LFS, 20-100kHz) has only been investigated significantly during the past two decades. Although HFS and LFS are...
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Introduction: Sonophoresis has been assessed as a novel approach to create skin permeability and drug delivery using low frequencies of ultrasound waves in the range of 20 kHz to 3 MHz. In this study, a system including seven 40 kHz piezoelectric transducers and an insulin chamber designed by the Medical Physics Research Center has been evaluated on hyperglycemic rabbits. Materials and Methods:...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutics
سال: 2014
ISSN: 2090-9918,2090-7818
DOI: 10.1155/2014/378048